5/25/2025
Last update
5/25/2025
Reviewed By
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 35 Reviews
8.5
Supplement Facts
Serving Size: 1 Level Teaspoon (approx. 2 g)
Serving Per Container: About 85
Amount Per Serving
%DV
Calories
10
Total Carbohydrate
2 g
<1%*
Total Sugars
2 g
â€
Organic D-Mannose
2 g (2,000 mg)
â€
Top Medical Research Studies
8
We explored the impact of D-mannose on intervertebral disc degeneration (IVDD), a condition often accompanied by significant pain. The study utilized various sophisticated methods to demonstrate that D-mannose acts primarily through a gene called TXNIP, which influences glutamine metabolism.
Though our findings suggest that D-mannose has promise in alleviating IVDD’s symptoms, we also acknowledge that it has not shown significant pain-relieving effects compared to traditional treatments. Further research may be needed to fully understand its therapeutic potential for pain management.
Though our findings suggest that D-mannose has promise in alleviating IVDD’s symptoms, we also acknowledge that it has not shown significant pain-relieving effects compared to traditional treatments. Further research may be needed to fully understand its therapeutic potential for pain management.
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Most Useful Reviews
9
Miracle solution
22 people found this helpful
Years of torment resolved with Mannosa! After suffering chronic cystitis for six years, the condition became unbearable with frequent infections and severe bone pain. Traditional treatments seemed futile, but after using Mannosa, my symptoms dwindled significantly within months. I took a small dosage before bed, and if I felt discomfort, a quick drink of Mannosa alleviated it immediately. Now I rarely use it, opting for prevention when needed, and I highly recommend it for anyone who shares this affliction.
Read More
9
Fast relief
22 people found this helpful
D-mannose has been a game changer for my chronic cystitis! I used to battle with persistent bone pain, but now, relief comes within a day of taking it. After a week, tests confirm all's clear! I even give it to my daughter, and her discomfort has vanished as well. This is the only remedy that works effectively for us.
Read More
9
Miracle product
15 people found this helpful
I was sceptical about D-Mannose, but it proved to be miraculous! After feeling intense bone pain and unable to get antibiotics, I tried the powder. To my surprise, after the first use, relief came quickly, and by the second day, I was pain-free. I now take it daily to prevent further UTIs.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
- All Researches
8
We explored the impact of D-mannose on intervertebral disc degeneration (IVDD), a condition often accompanied by significant pain. The study utilized various sophisticated methods to demonstrate that D-mannose acts primarily through a gene called TXNIP, which influences glutamine metabolism.
Though our findings suggest that D-mannose has promise in alleviating IVDD’s symptoms, we also acknowledge that it has not shown significant pain-relieving effects compared to traditional treatments. Further research may be needed to fully understand its therapeutic potential for pain management.
Though our findings suggest that D-mannose has promise in alleviating IVDD’s symptoms, we also acknowledge that it has not shown significant pain-relieving effects compared to traditional treatments. Further research may be needed to fully understand its therapeutic potential for pain management.
Read More
User Reviews
USERS' SCORE
Good
Based on 35 Reviews
8.5
- All Reviews
- Positive Reviews
- Negative Reviews
9
Miracle solution
22 people found this helpful
Years of torment resolved with Mannosa! After suffering chronic cystitis for six years, the condition became unbearable with frequent infections and severe bone pain. Traditional treatments seemed futile, but after using Mannosa, my symptoms dwindled significantly within months. I took a small dosage before bed, and if I felt discomfort, a quick drink of Mannosa alleviated it immediately. Now I rarely use it, opting for prevention when needed, and I highly recommend it for anyone who shares this affliction.
Read More
9
Fast relief
22 people found this helpful
D-mannose has been a game changer for my chronic cystitis! I used to battle with persistent bone pain, but now, relief comes within a day of taking it. After a week, tests confirm all's clear! I even give it to my daughter, and her discomfort has vanished as well. This is the only remedy that works effectively for us.
Read More
9
Miracle product
15 people found this helpful
I was sceptical about D-Mannose, but it proved to be miraculous! After feeling intense bone pain and unable to get antibiotics, I tried the powder. To my surprise, after the first use, relief came quickly, and by the second day, I was pain-free. I now take it daily to prevent further UTIs.
Read More
9
Relieves pain
9 people found this helpful
A fantastic solution for frequent urinary infections! It's not suitable for children, but it's a staple in my home. A small amount mixed in water provides quick relief from the pain associated with inflammation, and I've recommended it to many.
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10
Complete relief
7 people found this helpful
Having suffered from chronic attacks of cystitis for years, I decided to try this remedy. After three weeks, I've experienced no further attacks! I am hesitant to cease usage, as I feel like a complete person, free of pain and suffering, but I'm unsure how long to continue taking it.
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Frequently Asked Questions
8
Fast relief
1 people found this helpful
Works brilliantly, with noticeable effects in about two hours when I had pain from a bladder infection.
9
Fast relief
22 people found this helpful
D-mannose has been a game changer for my chronic cystitis! I used to battle with persistent bone pain, but now, relief comes within a day of taking it. After a week, tests confirm all's clear! I even give it to my daughter, and her discomfort has vanished as well. This is the only remedy that works effectively for us.
9
Miracle product
15 people found this helpful
I was sceptical about D-Mannose, but it proved to be miraculous! After feeling intense bone pain and unable to get antibiotics, I tried the powder. To my surprise, after the first use, relief came quickly, and by the second day, I was pain-free. I now take it daily to prevent further UTIs.
9
Quick effectiveness
1 people found this helpful
For anyone suffering from recurrent urinary tract infections, a half teaspoon in water followed by plenty of water can provide immediate relief from bone pain. Consistent use over a week makes a significant difference.
9
Pain relief noted
4 people found this helpful
After a month on Mannose, I felt a difference in my cystitis symptoms. Although I’m not completely cured, I stopped taking antibiotics due to immediate relief from bone pain in my lower abdomen. I prefer tablets, taking one level teaspoon. Wishing everyone good health!
7.5
Pain reduction achieved
2 people found this helpful
After almost three weeks of using D-Mannose Powder, my bladder pain has significantly reduced. I've struggled with bone pain and UTIs for 10 years, and this product, combined with cranberry capsules, gives me hope for a lasting solution.
7.5
Effective treatment
2 people found this helpful
Enduring cystitis was a nightmare, but after I switched to D-mannose at the recommendation of a doctor, I finally found relief from my agonising bone pain. Following the regimen improved my symptoms considerably within three days. The powder form is gentle on the stomach compared to capsules, making it an excellent choice.
9
Miracle solution
22 people found this helpful
Years of torment resolved with Mannosa! After suffering chronic cystitis for six years, the condition became unbearable with frequent infections and severe bone pain. Traditional treatments seemed futile, but after using Mannosa, my symptoms dwindled significantly within months. I took a small dosage before bed, and if I felt discomfort, a quick drink of Mannosa alleviated it immediately. Now I rarely use it, opting for prevention when needed, and I highly recommend it for anyone who shares this affliction.
10
Life-changing relief
4 people found this helpful
I have endured chronic bladder infections for a decade. Whenever I sense an infection, I take two spoons of D-Mannose, and the bone pain disappears by the next day. Thanks to D-Mannose, I've avoided antibiotics, which has truly transformed my life.
9
Highly recommend
4 people found this helpful
I often deal with IC and UTIs, finding d-mannose invaluable for managing flares and bladder health. When I experience that awful urgency, it works wonders. During severe episodes, I take it three to four times daily with vitamin C crystals, and within a few days, symptoms, including pain, settle down. I highly recommend it!
7.5
Rapid relief
4 people found this helpful
Suffering from cervical cystitis with blood in my urine, I found that this helps in tandem with cranberries. It alleviates severe symptoms within three days when taken twice daily in a smoothie or with cranberry capsules. I continue taking it for up to a month, as my acute pain subsides, adjusting my intake based on my wellbeing.
9
UTI protection noted
1 people found this helpful
I've been using this product to prevent UTIs and manage interstitial cystitis flares. It effectively alleviates bone pain and decreases the frequency of flares when I take a teaspoon every few hours.
10
No more pain
6 people found this helpful
Magic Mannose has been a game changer for my cystitis. After reading positive reviews, I started with the capsules, two nightly. I later switched to the powder for its cost-effectiveness. I've been taking it for 1.5 months now and note that previously persistent pain has not returned. Let's see how long this effect lasts; it's truly a worthwhile medication. Wishing everyone good health!
8
We explored the impact of D-mannose on intervertebral disc degeneration (IVDD), a condition often accompanied by significant pain. The study utilized various sophisticated methods to demonstrate that D-mannose acts primarily through a gene called TXNIP, which influences glutamine metabolism.
Though our findings suggest that D-mannose has promise in alleviating IVDD’s symptoms, we also acknowledge that it has not shown significant pain-relieving effects compared to traditional treatments. Further research may be needed to fully understand its therapeutic potential for pain management.
Though our findings suggest that D-mannose has promise in alleviating IVDD’s symptoms, we also acknowledge that it has not shown significant pain-relieving effects compared to traditional treatments. Further research may be needed to fully understand its therapeutic potential for pain management.
References
- Dong ZL, Jiao X, Wang ZG, Yuan K, Yang YQ, et al. D-mannose alleviates intervertebral disc degeneration through glutamine metabolism. Mil Med Res. 2024;11:28. 10.1186/s40779-024-00529-4
